Zimecterin Paste is a broad-spectrum dewormer that controls 35 stages and species of worms and bots in horses.

Indications: Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. ZIMECTERIN (ivermectin) Paste provides effective control of the following parasites in horses: Large strongyles (adults) - Strongylus vulgaris (also early forms in blood vessels), S edentalus (also tissue stages), S equinus, Triodontophorus spp; Small strongyles including those resistant to some benzimidazole class compounds (adults and fourth-stage larvae) - Cyathostomum spp, Cylicocyclus spp, Cylicostephanus spp, Cylicodontophorus spp; Pinworms (adults and fourth-stage larvae) - Oxyuris equi; Ascarids (adults and third- and fourth-stage larvae) - Parascaris equorum; Hairworms (adults) - Trichostrogylus axei; Large-mouth Stomach Worms (adults) - Habronema muscae; Bots (oral and gastric stages) - Gastrophilus spp; Lungworms (adults and forth-stage larvae) - Dictyocaulus arnfieldi; Intestinal Threadworms (adults) - Strongyloides westeri; Summer Sores caused by Habronema and Draschia spp cutaneous third-stage larvae; Dermatitis caused by neck threadworm microfilarie, Onchocerca sp.

Dosage and Administration: The syringe contains sufficient paste to treat one 1250 lb horse at the recommended dose rate of 91 mcg ivermectin per lb (200 mcg/kg) body weight. Each weight marking on the syringe plunger delivers enough paste to treat 250 lb body weight.
(1) While holding plunger, turn the knurled ring on the plunger turn to the left and slide it so the side nearest the barrel is at the prescribed weight marking. (2) Lock the ring in place by making a turn to the right. (3) Make sure that the horse's mouth contains no feed. (4) Remove the cover from the tip of the syringe. (5) Insert the syringe tip into the horse's mouth at the space between the teeth. (6) Depress the plunger as far as it will go, depositing paste on the back of the tongue. (7) Immediately raise the horse's head for a few seconds after dosing.

Discussion:
Parasite Control Program: All horses should be included in a regular parasite control program with particular attention being paid to mares, foals and yearlings. Foals should be treated initially at 6 to 8 weeks of age, and routine treatment repeated as appropriate. Consult your veterinarian for a control program to meet your specific needs. ZIMECTERIN (ivermectin) Paste effectively controls gastrointestinal nematodes and bots of horses. Regular treatment will reduce the chances of verminous arteritis caused by S vulgaris.
Product Advantages: Broad-spectrum control, ZIMECTERIN Paste kills important internal parasites, including bots and the arterial stages of Strongyles vulgaris, with a single dose. ZIMECTERIN Paste is a potent anti-parasitic agent that is neither a benzimidazole nor an organophosphate.

Precautions: Ivermectin and excreted ivermectin residues may adversely affect aquatic organisms. Do not contaminate ground or surface water. Dispose of the ZIMECTERIN (ivermectin) Paste syringe in an approved landfill or by incineration.

Cautions: ZIMECTERIN (ivermectin) Paste has been formulated specifically for use in horses only. This product should not be used in other animal species as severe reactions, including fatalities in dogs, may result.
Note to User: Swelling and itching reactions after treatment with ZIMECTERIN Paste have occurred in horses carrying heavy infections of neck threadworm (Onchocerca sp) microfiliariae. These reactions were most likely the result of microfiliarae dying in large numbers. Symptomatic treatment may be advisable. Consult your veterinarian should any such reactions occur. Healing of summer sores involving extensive tissue changes may require other appropriate therapy in conjunction with treatment with ZIMECTERIN (ivermectin) Paste. Reinfection, and measures for its prevention, should also be considered. Consult your veterinarian if the condition does not improve.

Warnings: Do not use on horses intended for food purposes.
Refrain from smoking and eating when handling. Wash hands after use. Avoid contact with eyes. Keep this and all drugs out of the reach of children.
Side Effects: Safety - ZIMECTERIN (ivermectin) Paste may be used in horses of all ages, including mares at any stage of pregnancy. Stallions may be treated without adversely affecting their fertility.