Thiol-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 194425-46-2

Molecular Weight: 298.40

Formula: C12H26O6S

Chemical Name: 17-sulfanyl-3,6,9,12,15-pentaoxaheptadecan-1-ol

Smiles: OCCOCCOCCOCCOCCOCCS

InChiKey: RBHVCADZZSNWRE-UHFFFAOYSA-N

InChi: InChI=1S/C12H26O6S/c13-1-2-14-3-4-15-5-6-16-7-8-17-9-10-18-11-12-19/h13,19H,1-12H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.