S49076 hydrochloride is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.

Product information

CAS Number: 1265966-31-1

Molecular Weight: 474.96

Formula: C22H23ClN4O4S

Chemical Name: 3-{[(3Z)-3-({4-[(morpholin-4-yl)methyl]-1H-pyrrol-2-yl}methylidene)-2-oxo-2, 3-dihydro-1H-indol-5-yl]methyl}-1, 3-thiazolidine-2, 4-dione hydrochloride

Smiles: Cl.O=C1SCC(=O)N1CC1C=CC2NC(=O)/C(=C\C3=CC(CN4CCOCC4)=CN3)/C=2C=1

InChiKey: FPSAJUOIYZSJJA-NAIZSXBXSA-N

InChi: InChI=1S/C22H22N4O4S.ClH/c27-20-13-31-22(29)26(20)12-14-1-2-19-17(8-14)18(21(28)24-19)9-16-7-15(10-23-16)11-25-3-5-30-6-4-25;/h1-2,7-10,23H,3-6,11-13H2,(H,24,28);1H/b18-9-;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.