SSX2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12941-50, ES12941-100

Citations, Manuals and MSDS Available upon request.

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t (X; 18) (p11.2; q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human SSX2 AA range: 16-66

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 6757

Human SWISS Prot NO: Q16385

Subcellular Location: Nucleus

Research Use Only