Z-Ile-Leu-al is a cell-permeable, reversible inhibitor of γ-secretase. It acts by reducing amyloid β (Aβ)-production by blocking γ-secretase activity in vitro.

Product information

CAS Number: 161710-10-7

Molecular Weight: 362.46

Formula: C20H30N2O4

Synonym:

Z-IL-CHO

GSI-XII

γ-Secretase inhibitor XII

Chemical Name: benzyl N-[(1S,2S)-2-methyl-1-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}butyl]carbamate

Smiles: CC(C)C[C@@H](C=O)NC(=O)[C@@H](NC(=O)OCC1C=CC=CC=1)[C@@H](C)CC

InChiKey: WJQLUFQGNVGLKR-SZMVWBNQSA-N

InChi: InChI=1S/C20H30N2O4/c1-5-15(4)18(19(24)21-17(12-23)11-14(2)3)22-20(25)26-13-16-9-7-6-8-10-16/h6-10,12,14-15,17-18H,5,11,13H2,1-4H3,(H,21,24)(H,22,25)/t15-,17-,18-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.