5(6)-TAMRA contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.

Product information

CAS Number: 246256-50-8

Molecular Weight: 527.52

Formula: C58H50N6O14

Synonym:

5(6)-Carboxytetramethylrhodamine N-succinimidyl ester

Chemical Name: 9-(2-carboxylato-4(or 5)-{[(2, 5-dioxopyrrolidin-1-yl)oxy]carbonyl}phenyl)-3, 6-bis(dimethylamino)-10-xanthen-10-ylium

Smiles: CN(C)C1C=C2[O+]=C3C=C(C=CC3=C(C2=CC=1)C1=CC=C(C=C1C([O-])=O)C(=O)ON1C(=O)CCC1=O)N(C)C.CN(C)C1=CC2=[O+]C3=CC(=CC=C3C(C3=CC(=CC=C3C([O-])=O)C(=O)ON3C(=O)CCC3=O)=C2C=C1)N(C)C

InChiKey: PZJJMXHEFZZNPB-UHFFFAOYSA-N

InChi: InChI=1S/2C29H25N3O7/c1-30(2)17-6-9-20-23(14-17)38-24-15-18(31(3)4)7-10-21(24)27(20)22-13-16(5-8-19(22)28(35)36)29(37)39-32-25(33)11-12-26(32)34;1-30(2)17-6-9-20-23(14-17)38-24-15-18(31(3)4)7-10-21(24)27(20)19-8-5-16(13-22(19)28(35)36)29(37)39-32-25(33)11-12-26(32)34/h2*5-10,13-15H,11-12H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 25 mg/mL (47.39 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Fuller ME, et al. Application of a vital fluorescent staining method for simultaneous, near-real-time concentration monitoring of two bacterial strains in an Atlantic coastal plain aquifer in Oyster, Virginia. Appl Environ Microbiol. 2004 Mar;70(3):1680-7.
2. Brunner A, et al. Labelling peptides with fluorescent probes for incorporation into degradable polymers. Eur J Pharm Biopharm. 1998 May;45(3):265-73.
3. Jiang M, et al. Design and synthesis of new acid cleavable linkers for DNA sequencing by synthesis. Nucleosides Nucleotides Nucleic Acids. 2014;33(12):774-85.

Products are for research use only. Not for human use.